Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thioacetamide | HCID 2723949 | — |
| Reactant | 3-[3-Bromo-4-(bromomethyl)phenyl]-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole | HCID 86643371 | — |
| Product | HCID 86643377 | HCID 86643377 | 32.1% |
Reaction Steps
3-[3-bromo-4-(bromomethyl)phenyl]-5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole (0.3 g) was mixed with thioacetamide (0.04 g), and the mixture was then stirred for one hour at 80° C. The residue was purified by silica gel chromatography to yield N-{2-bromo-4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl]benzyl}ethanethioamide (0.09 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08372867B2 |
|---|
| Source dataset | uspto-grants-2013_02 |
|---|
| ORD ID | ord-c7c9b60df562482a8581046a97e83b49 |
|---|
| Source note | uspto-grants-2013_02 |
|---|
