Dicyclohexylcarbodiimide → 2,3-Dicyclohexyl-1-methyl-1-(3-(trimethoxysilyl)propyl)guanidine

Participants

Reaction Steps

A mixture of 23.23 g of N-methyl-(3-(trimethoxysilyl)propyl)amine (0.12 mol, 20% excess) and of 20.65 g of dicyclohexylcarbodiimide (0.1 mol) was heated for 6 h at 100° C. (carbodiimide conversion of 94%). The final colorless mixture was devolatilized at 100° C. under 2 mbar for 2 h to give 41.3 g of a colorless, moderately viscous liquid corresponding to the expected guanidine, containing 6% of the initial amine.

Provenance & Evidence