HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 3870Generated: October 26, 2026
Potassium Hydroxide → 8-(2-Methoxy-4-benzyloxy-phenyl)-2-benzyloxypurine
https://huagongshe.com/reaction/3870
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 8-(2-Methoxy-4-benzyloxy-phenyl)-2-chloro-purine | HCID 13532386 | — |
| Solvent | Benzyl Alcohol | HCID 244 | — |
| Product | 8-(2-Methoxy-4-benzyloxy-phenyl)-2-benzyloxypurine | HCID 13532399 | — |
Reaction Steps
An amount of 4.5 gm of powdered potassium hydroxide is dissolved in 70 ml of benzyl alcohol, and then 7.2 gm of 8-(2-methoxy-4-benzyloxy-phenyl)-2-chloro-purine are added. The mixture is heated to 150° C. for three hours, cooled, and filtered, the filtrate is mixed with ether, and the precipitate obtained is purified by chromatography on silica gel [eluant: methylene chloride/ethanol (100:2.5)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04722929 |
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| Source dataset | uspto-grants-1988_02 |
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| ORD ID | ord-18a6059416844248a8ba411c923fd244 |
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| Source note | uspto-grants-1988_02 |
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