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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 38700Generated: October 26, 2026

Methyl 2-(4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate → {2'-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

https://huagongshe.com/reaction/38700

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetateHCID 46739456—
ReactantBenzyl-ethyl-carbamic acid 2-bromo-5-trifluoromethyl-benzyl esterHCID 67430273—
Product{2'-[(Benzyl-ethyl-carbamoyloxy)-methyl]-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl esterHCID 67430680—

Reaction Steps

Prepared according to the procedure described in Example 15, Step 3, using the following starting materials: [4-fluoro-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid methyl ester and benzyl-ethyl-carbamic acid 2-bromo-5-trifluoromethyl-benzyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524748B2
Source datasetuspto-grants-2013_09
ORD IDord-7884ef070ce649e9aa6596086abf5c3b
Source noteuspto-grants-2013_09