HuagongsheHuagongshe Chemistry Print Report · For research reference only
8-(2-Methoxy-4-aminocarbonyl-phenyl)-1H,3H-purin-2,6-dione → 8-(2-Methoxy-4-cyano-phenyl)-1H,3H-purin-2,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8-(2-Methoxy-4-aminocarbonyl-phenyl)-1H,3H-purin-2,6-dione | HCID 20153243 | — |
| Solvent | Phosphorus oxychloride | HCID 24813 | — |
| Product | 8-(2-Methoxy-4-cyano-phenyl)-1H,3H-purin-2,6-dione | HCID 20153256 | — |
Reaction Steps
Prepared by boiling 0.7 gm of 8-(2-methoxy-4-aminocarbonylphenyl)-1H,3H-purin-2,6-dione in 10 ml of phosphorus oxychloride for 24 hours. The compound crystallizes as the hemihydrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04722929 |
| Source dataset | uspto-grants-1988_02 |
| ORD ID | ord-659dfef79a1345f9a27aa0d9cf9068c9 |
| Source note | uspto-grants-1988_02 |