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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 387944Generated: October 30, 2026

HCID 22936653, compound → HCID 22936372, compound

https://huagongshe.com/reaction/387944

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22936653HCID 22936653—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22936372HCID 22936372107.9%

Reaction Steps

After dissolving 6-carbamoyl-4-(3-trifluoromethyl-4-nitrophenoxy)-7-methoxyquinoline (0.60 g) in tetrahydrofuran (10 ml) and methanol (10 ml), the solution was subjected to catalytic reduction with palladium-carbon (600 mg) for 10 hours under a hydrogen atmosphere to obtain the title compound (0.60 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08372981B2
Source datasetuspto-grants-2013_02
ORD IDord-bd6dd26f9d49488d92bf1fca9b792654
Source noteuspto-grants-2013_02