HCID 22936659, compound → HCID 22936943, compound

HRID 387963Notes

Reaction equation

HRID 387963 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[C:13]#[N:14])[N:9]=[CH:8][CH:7]=[C:6]2[O:15][C:16]1[CH:21]=[CH:20][C:19]([N+:22]([O-])=O)=[CH:18][CH:17]=1>[Fe]>[NH2:22][C:19]1[CH:18]=[CH:17][C:16]([O:15][C:6]2[C:5]3[C:10](=[CH:11][C:12]([C:13]#[N:14])=[C:3]([O:2][CH3:1])[CH:4]=3)[N:9]=[CH:8][CH:7]=2)=[CH:21][CH:20]=1

Participants

3

Reactant 1

HCID 22936659HCID 22936659, compound

Product 1

HCID 22936943HCID 22936943, compoundYield 68.5%

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

6-Methoxy-4-(4-nitrophenoxy)quinoline-7-carbonitrile (290 mg) was subjected to iron reduction by the same method as in Production Example 10 to obtain the title compound (180 mg).

Sources & evidence

ORD record
ord-8e278d6f1848445aa65c913752b2532c
Source dataset
uspto-grants-2013_02
Patent number
US08372981B2

Reaction notes

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