HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 387967Generated: October 30, 2026
HCID 67202400, compound → Methyl 4-hydroxyfuro[2,3-B]pyridine-2-carboxylate
https://huagongshe.com/reaction/387967
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 67202400 | HCID 67202400 | — |
| Solvent | 1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) | HCID 24670 | — |
| Product | Methyl 4-hydroxyfuro[2,3-B]pyridine-2-carboxylate | HCID 58931135 | 76.4% |
Reaction Steps
After adding 5-[(2,2-dimethyl-4,6-dioxo-[1.3]dioxan-5-ylidenemethyl)amino]furan-2-carboxylic acid methyl ester (4.0 g) to Dowtherm A (30 ml), the mixture was heated and stirred at 200° C. for 1 hour. After cooling, the precipitated crystals were filtered out and washed with diethyl ether to obtain the title compound (2.0 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08372981B2 |
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| Source dataset | uspto-grants-2013_02 |
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| ORD ID | ord-f84f90df17694c9b941f6f8a323e5a1f |
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| Source note | uspto-grants-2013_02 |
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