HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Nitrophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester → 4-(4-Aminophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Nitrophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester | HCID 58931497 | — |
| Catalyst | Iron | HCID 23925 | — |
| Product | 4-(4-Aminophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester | HCID 58931462 | 86.9% |
Reaction Steps
4-(4-Nitrophenoxy)-furo[2,3-b]pyridine-2-carboxylic acid methyl ester (70 mg) was subjected to iron reduction by the same method as in Production Example 10 to obtain the title compound (55 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08372981B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-83b0dcbffd874c94bf3da17223e2f72d |
| Source note | uspto-grants-2013_02 |