2-Methoxypyridine-3,4-diamine → HCID 70420390, compound

HRID 3883Notes

Reaction equation

HRID 3883 reaction equation
C[O:2][C:3]1[C:8]([NH2:9])=[C:7]([NH2:10])[CH:6]=[CH:5][N:4]=1.CO[C:13]1[CH:21]=[C:20]([C:22]#N)[CH:19]=[CH:18][C:14]=1[C:15]([OH:17])=[O:16].[Cl:24][CH:25](Cl)C.[CH2:28]([OH:30])C>>[ClH:24].[CH3:28][O:30][C:21]1[CH:13]=[C:14]([C:15]([O:17][CH3:25])=[O:16])[CH:18]=[CH:19][C:20]=1[C:22]1[N:9]=[C:8]2[C:3](=[O:2])[NH:4][CH2:5][CH:6]=[C:7]2[N:10]=1

Participants

4

Reactant 3

HCID 101489982-Methoxypyridine-3,4-diamineHCID 151660044-Cyano-2-methoxybenzoic acidHCID 18381953Dichloroethane ethanol

Product 1

HCID 70420390HCID 70420390, compound

Procedure

Prepared analogously to Example 1 from 2-methoxy-3,4-diaminopyridine and 2-methoxy-4-cyano-benzoic acid. The product mixture obtained is digested with dichloroethane/ethanol (3:1). The undissolved material is filtered off, and the solution is evaporated and boiled with methanolic hydrochloric acid. On cooling, the product crystallizes out in the form of the hydrate.

Workup

  1. customThe product mixture obtained
  2. filtrationThe undissolved material is filtered off
  3. customthe solution is evaporated
  4. temperatureOn cooling
  5. customthe product crystallizes out in the form of the hydrate

Sources & evidence

ORD record
ord-1bcc2a3d16bb4766b58a295e2fc2fc6b
Source dataset
uspto-grants-1988_02
Patent number
US04722929

Reaction notes

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