HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxypyridine-3,4-diamine → 2-(2-Methoxy-4-methoxycarbonyl-phenyl)-5H-imidazo[4,5-c]pyridin-4-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxypyridine-3,4-diamine | HCID 10148998 | — |
| Reactant | 4-Cyano-2-methoxybenzoic acid | HCID 15166004 | — |
| Reactant | Dichloroethane ethanol | HCID 18381953 | — |
| Product | 2-(2-Methoxy-4-methoxycarbonyl-phenyl)-5H-imidazo[4,5-c]pyridin-4-one hydrochloride | HCID 70420390 | — |
Reaction Steps
Prepared analogously to Example 1 from 2-methoxy-3,4-diaminopyridine and 2-methoxy-4-cyano-benzoic acid. The product mixture obtained is digested with dichloroethane/ethanol (3:1). The undissolved material is filtered off, and the solution is evaporated and boiled with methanolic hydrochloric acid. On cooling, the product crystallizes out in the form of the hydrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04722929 |
| Source dataset | uspto-grants-1988_02 |
| ORD ID | ord-1bcc2a3d16bb4766b58a295e2fc2fc6b |
| Source note | uspto-grants-1988_02 |