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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 388407Generated: October 29, 2026

4-Piperidone → HCID 57821257, compound

https://huagongshe.com/reaction/388407

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PiperidoneHCID 33721—
ReactantEthyl 2-(chloromethyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylateHCID 2339310—
ProductHCID 57821257HCID 57821257—

Reaction Steps

Using ethyl 2-chloromethyl-5-methyl-4-oxo-3,4-dihydrothieno-[2,3-d]pyrimidine-6-carboxylate and piperidin-4-one, a substitution reaction was carried out similarly to later appearing Production Example 21. Successively the reaction product was hydrolyzed similarly to Example 33, without intervening isolation of the reaction product, to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08377944B2
Source datasetuspto-grants-2013_02
ORD IDord-0746f51183fd4898883ea8539c3cf10f
Source noteuspto-grants-2013_02