Hydrogen Bromide → HCID 68664078, compound

HRID 388410Notes

Reaction equation

HRID 388410 reaction equation
C(OC([CH:11]([NH2:27])[CH2:12][C:13]1[NH:14][C:15](=[O:26])[C:16]2[C:21]([CH3:22])=[C:20]([C:23]([OH:25])=[O:24])[S:19][C:17]=2[N:18]=1)=O)C1C=CC=CC=1.[BrH:28]>>[BrH:28].[NH2:27][CH2:11][CH2:12][C:13]1[NH:14][C:15](=[O:26])[C:16]2[C:21]([CH3:22])=[C:20]([C:23]([OH:25])=[O:24])[S:19][C:17]=2[N:18]=1

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 69077070HCID 69077070, compound

Product 1

HCID 68664078HCID 68664078, compound

Procedure

A mixture of 387 mg of so obtained 2-(2-benzyloxycarbonyl-aminoethyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylic acid and 4.5 mL of hydrobromic acid was stirred at room temperature for 3 hours, and thereafter the solvent was distilled off under reduced pressure to provide 410 mg (quantitative) of the title compound.

Workup

  1. distillationthe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-6738cbcc47d6475fbd56afca7c9f166b
Source dataset
uspto-grants-2013_02
Patent number
US08377944B2

Reaction notes

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