反应详情

A mixture of (R)-cyclohexyl-(2-nitro-benzoylamino)-acetic acid methyl ester (1.16 g, 3.62 mmol), 10% Pd/C (250 mg) in EtOH (25 mL) are stirred under H2 atmosphere at room temperature for 16 hours. The reaction mixture is filtered and the organic layer is concentrated to give (R)-(2-amino-benzoylamino)-cyclohexyl-acetic acid methyl ester (1.08 g, 98%).

1. filtrationThe reaction mixture is filtered
2. concentrationthe organic layer is concentrated