HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide → n-(6-Acetyl-3-chloro-4-methoxyphenyl)-4-isopropylthiazole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide | HCID 20773655 | — |
| Reactant | 4-(Propan-2-yl)-1,3-thiazole-2-carbonyl chloride | HCID 57578796 | — |
| Reactant | 1-(2-Amino-4-chloro-5-methoxyphenyl)ethanone | HCID 66650482 | — |
| Product | n-(6-Acetyl-3-chloro-4-methoxyphenyl)-4-isopropylthiazole-2-carboxamide | HCID 66650598 | 69% |
Reaction Steps
N-(6-Acetyl-3-chloro-4-methoxyphenyl)-4-isopropylthiazole-2-carboxamide 217g was synthesized from compounds 201g and 214 as a beige solid in 69% yield, according to the procedure as described for compound 217a. MS (ESI, EI+): m/z=354 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08377962B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-911cc55696054611aa92c085c1a0ef8f |
| Source note | uspto-grants-2013_02 |