Hydrochloric Acid → HCID 86620343, compound

Participants

Reaction Steps

A solution of ethyl-3-[2-(methylamino)-1,3-thiazol-4-yl]isoxazole-3-carboxylate (65 mg, 0.26 mmol) in ethanol (3.0 mL) was treated with 1N aqueous sodium hydroxide (0.30 mL, 0.28 mmol) and the mixture was stirred at room temperature for 2 h. The mixture was neutralized with 1 N aqueous hydrochloric acid and concentrated in vacuo to give the crude which was used without purification. MF=C8H7N3O3S; LCMS calculated for C8H7N3O3S (M+H)+: m/z=226.

Provenance & Evidence