Sodium Iodide → HCID 66732740, compound

HRID 389002Notes

Reaction equation

HRID 389002 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[I-].[Na+].[OH-].[Na+].Cl[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][OH:27]>O>[C:3]1([C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[O:1][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][OH:27]

Participants

6

Reactant 4

HCID 5238Sodium IodideHCID 7017(1,1'-Biphenyl)-2-olHCID 14798Sodium HydroxideHCID 900121-Octanol, 8-chloro-

Product 1

HCID 66732740HCID 66732740, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The compound was prepared using essentially the procedure of Preparatory Example 1 with 2-hydroxy biphenyl (40 g.), water (250 g.), sodium iodide (3.5 g.) and sodium hydroxide (37.6 g. of 50% in water). This mixture was heated to 100° C. with agitation and 8-chloro-1-octanol (77.4 g.) was added. The product was recovered essentially as in Preparatory Example 1.

Workup

  1. customThe compound was prepared
  2. additionwas added
  3. customThe product was recovered essentially as in Preparatory Example 1

Sources & evidence

ORD record
ord-05054416c02248f89e5b132dca5599b6
Source dataset
uspto-grants-2013_02
Patent number
US08378046B2

Reaction notes

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