2-Methoxyethylamine → HCID 44469737, compound

HRID 38921Notes

Reaction equation

HRID 38921 reaction equation
CC1C=CC(S(O[CH2:12][CH:13]2[O:18][C:17]3[CH:19]=[C:20]([S:23]([CH3:26])(=[O:25])=[O:24])[CH:21]=[CH:22][C:16]=3[O:15][CH2:14]2)(=O)=O)=CC=1.[CH3:27][O:28][CH2:29][CH2:30][NH2:31]>C(#N)C>[CH3:27][O:28][CH2:29][CH2:30][NH:31][CH2:12][CH:13]1[O:18][C:17]2[CH:19]=[C:20]([S:23]([CH3:26])(=[O:24])=[O:25])[CH:21]=[CH:22][C:16]=2[O:15][CH2:14]1

Participants

4

Reactant 2

HCID 80182-MethoxyethylamineHCID 86652933[7-(Methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate

Product 1

HCID 44469737HCID 44469737, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Preparation according to Example 25 using [7-(methylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methyl 4-methylbenzenesulfonate (0.018 g, 0.046 mmol), 2-methoxyethanamine (0.5 ml), ACN (3 ml). MS m/z (rel. intensity, 70 eV) 301 (M+, 2), 256 (19), 88 (bp), 56 (12), 58 (7).

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-ac7515f4df5a4d099326fca6659195ef
Source dataset
uspto-grants-2013_09
Patent number
US08524766B2

Reaction notes

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