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HRID389239

反应详情

EQUATION

反应方程式

HRID 389239 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)C(C)C
HCID11251

3-Methyl-2-butanone

C5H10O

结构：COc1ccc(NN)cc1.Cl
HCID2723904

4-Methoxyphenylhydrazine hydrochloride

C7H11ClN2O

PRODUCTS

生成物

1
结构：COc1ccc2c(c1)C(C)(C)C(C)=N2
HCID11095392

5-Methoxy-2,3,3-trimethyl-3H-indole

C12H15NO

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

CONDITIONS

反应条件

温度
10 °C

PROCEDURE

实验过程

To 4-methoxyphenyl hydrazine hydrochloride (4.84 g) was added 3-methyl-2-butanone (6.4 ml) and acetic acid (45 ml). The mixture was heated to 10° C. for 2.5 hours after which time the solvent was removed by rotary evaporation. Flash column chromatography gave the product (4.66 g).

WORKUP

后处理

  1. customwas removed by rotary evaporation