Triethylamine → HCID 58579953, compound

HRID 389270Notes

Reaction equation

HRID 389270 reaction equation
[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([C:14]2[C:19]([CH2:20][NH:21][CH2:22][CH3:23])=[CH:18][C:17]([CH3:24])=[CH:16][N:15]=2)[CH:7]=1)[CH3:2].FC(F)(F)C([O-])=O.[C:33](Cl)(=[O:42])[CH2:34][CH2:35][C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1.C(N(CC)CC)C>C(Cl)Cl>[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([C:14]2[C:19]([CH2:20][N:21]([CH2:22][CH3:23])[C:33](=[O:42])[CH2:34][CH2:35][C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)=[CH:18][C:17]([CH3:24])=[CH:16][N:15]=2)[CH:7]=1)[CH3:2]

Participants

6

Reactant 4

HCID 8471TriethylamineHCID 64801Benzenepropanoyl chlorideHCID 84468TrifluoroacetateHCID 58579969HCID 58579969, compound

Product 1

HCID 58579953HCID 58579953, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

[3-(3-Ethylaminomethyl-5-methyl-pyridin-2-yl)-4-methoxy-phenyl]-acetic acid ethyl ester, trifluoroacetate (0.36 mmol) was reacted with hydrocinnamoyl chloride (0.06 mL, 0.44 mmol) and triethylamine (0.15 mL, 1.09 mmol) in CH2Cl2 to give the title compound.

Sources & evidence

ORD record
ord-b7e6d3fe35464e6c9f0f31e74860907f
Source dataset
uspto-grants-2013_02
Patent number
US08378107B2

Reaction notes

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