Lithium Hydroxide → HCID 45109847, compound

HRID 389271Notes

Reaction equation

C([O:3][C:4](=[O:35])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([C:14]2[C:19]([CH2:20][N:21]([CH2:32][CH3:33])[C:22](=[O:31])[CH2:23][CH2:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)=[CH:18][C:17]([CH3:34])=[CH:16][N:15]=2)[CH:7]=1)C.[Li+].[OH-]>>[CH2:32]([N:21]([CH2:20][C:19]1[C:14]([C:8]2[CH:7]=[C:6]([CH2:5][C:4]([OH:35])=[O:3])[CH:11]=[CH:10][C:9]=2[O:12][CH3:13])=[N:15][CH:16]=[C:17]([CH3:34])[CH:18]=1)[C:22](=[O:31])[CH2:23][CH2:24][C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[CH3:33]

Participants

Reactant 2

HCID 3939Lithium Hydroxide

HCID 58579953HCID 58579953, compound

Product 1

HCID 45109847HCID 45109847, compound

Procedure

[3-(3-{[Ethyl-(3-phenyl-propionyl)-amino]-methyl}-5-methyl-pyridin-2-yl)-4-methoxy-phenyl]-acetic acid ethyl ester was hydrolyzed with 1N aqueous LiOH to give the title compound.

Sources & evidence

ORD record: ord-0c0cfd4e9d1c412ca9d72f3812349399
Source dataset: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08378107B2

Reaction notes

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