Lithium Hydroxide → HCID 45255231, compound

HRID 389273Notes

Reaction equation

HRID 389273 reaction equation
C([O:3][C:4](=[O:35])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([C:14]2[C:19]([CH2:20][N:21]([CH2:32][CH3:33])[C:22]([NH:24][CH2:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)=[O:23])=[CH:18][C:17]([CH3:34])=[CH:16][N:15]=2)[CH:7]=1)C.[Li+].[OH-]>>[CH2:25]([NH:24][C:22](=[O:23])[N:21]([CH2:20][C:19]1[C:14]([C:8]2[CH:7]=[C:6]([CH2:5][C:4]([OH:35])=[O:3])[CH:11]=[CH:10][C:9]=2[O:12][CH3:13])=[N:15][CH:16]=[C:17]([CH3:34])[CH:18]=1)[CH2:32][CH3:33])[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

Participants

3

Reactant 2

HCID 3939Lithium HydroxideHCID 67994244HCID 67994244, compound

Product 1

HCID 45255231HCID 45255231, compound

Procedure

{3-[3-(3-Benzyl-1-ethyl-ureidomethyl)-5-methyl-pyridin-2-yl]-4-methoxy-phenyl}-acetic acid ethyl ester was hydrolyzed with 1N aqueous LiOH to give the title compound.

Sources & evidence

ORD record
ord-a72c4c75d5a94c1486e53df9c4ade465
Source dataset
uspto-grants-2013_02
Patent number
US08378107B2

Reaction notes

Loading…