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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 389276Generated: October 30, 2026

Hydrochloric Acid → HCID 131730234, compound

https://huagongshe.com/reaction/389276

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58579957HCID 58579957—
SolventDichloromethaneHCID 6344—
ProductHCID 131730234HCID 131730234—

Reaction Steps

(3-{3-[(tert-Butoxycarbonyl-ethyl-amino)-methyl]-quinolin-2-yl}-4-methoxy-phenyl)-acetic acid ethyl ester (1.18 g, 2.46 mmol) in CH2Cl2 (10 mL) was treated with hydrogen chloride (4N in 1,4-dioxane; 5 mL, 20.0 mmol) at room temperature for 3 hours. The mixture was concentrated to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08378107B2
Source datasetuspto-grants-2013_02
ORD IDord-32cbf3aef78c45da86b952a081d7049a
Source noteuspto-grants-2013_02