Cyclopropanecarbonyl chloride → HCID 58579959, compound

HRID 389284Notes

Reaction equation

Cl.Cl.[CH2:3]([O:5][C:6](=[O:30])[CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([C:16]2[C:17]([CH2:26][NH:27][CH2:28][CH3:29])=[N:18][C:19]3[C:24]([CH:25]=2)=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH:9]=1)[CH3:4].[CH:31]1([C:34](Cl)=[O:35])[CH2:33][CH2:32]1>>[CH2:3]([O:5][C:6](=[O:30])[CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[C:10]([C:16]2[C:17]([CH2:26][N:27]([C:34]([CH:31]3[CH2:33][CH2:32]3)=[O:35])[CH2:28][CH3:29])=[N:18][C:19]3[C:24]([CH:25]=2)=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH:9]=1)[CH3:4]

Participants

Reactant 2

HCID 77637Cyclopropanecarbonyl chloride

HCID 131730235HCID 131730235, compound

Product 1

HCID 58579959HCID 58579959, compound

Procedure

Prepared according to the procedure described in Example 5, Step 5, using the following starting materials: [3-(2-ethylaminomethyl-quinolin-3-yl)-4-methoxy-phenyl]-acetic acid ethyl ester, dihydrochloride and cyclopropanecarbonyl chloride.

Workup

customPrepared

Sources & evidence

ORD record: ord-a91b6cb9ae9e4f23a2b91233eeb0f39e
Source dataset: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08378107B2

Reaction notes

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