反应详情

温度

5 °C

To the clear solution of 4,7-Dimethoxyindane (22.5 gm, 0.126 mole) in Methylene chloride (400 ml), added Boron tribromide (12.27 ml, 0.13 mole) at 0° C. After 2 hours stirring at 0-10° C., water (100 ml) was added and then the reaction mixture was extracted with Methylene chloride. The Methylene chloride layer was dried over Sodium sulphate and distilled off to give a crude mass which was purified by column chromatography using 7% Ethyl acetate in Hexane (9.0 gm).

1. extractionthe reaction mixture was extracted with Methylene chloride
2. dry with materialThe Methylene chloride layer was dried over Sodium sulphate
3. distillationdistilled off
4. customto give a crude mass which
5. customwas purified by column chromatography