4-Iodo-2-(isoquinolin-5-yl)furo[2,3-c]pyridin-7-amine → 2-(1-Benzothiophen-7-yl)-4-iodofuro[2,3-c]pyridin-7-amine

Participants

Role	Name	HCID	Charge
Reactant	4-Iodo-2-(isoquinolin-5-yl)furo[2,3-c]pyridin-7-amine	HCID 66759474	—
Reactant	2-(1-Benzothiophen-7-yl)furo[2,3-c]pyridin-7-amine	HCID 66760270	—
Product	2-(1-Benzothiophen-7-yl)-4-iodofuro[2,3-c]pyridin-7-amine	HCID 66759975	51%

Reaction Steps

The title compound was prepared in 51% yield from 2-(1-benzothiophen-7-yl)furo[2,3-c]pyridin-7-amine by a procedure analogous to Intermediate 10, Step B. 1H NMR (300 MHz, DMSO-d6) δ 8.20 (d, J=7.5 Hz, 1H), 8.01 (d, J=7.6 Hz, 1H), 7.95 (d, J=1.5 Hz, 2H), 7.64-7.58 (m, 2H). 7.18 (s, 1H). 6.67 (br s, 2H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08378104B2
Source dataset	uspto-grants-2013_02
ORD ID	ord-c126ca1747fb473e86aa382492d6784f
Source note	uspto-grants-2013_02