HRID389569

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)OC(=O)N1CC(n2cc(B3OC(C)(C)C(C)(C)O3)cn2)C1

HCID54576812

tert-Butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidine-1-carboxylate

C17H28BN3O4

HCID66760274

未命名化合物

PRODUCTS

生成物

结构：Nc1ncc(-c2cnn(C3CNC3)c2)c2cc(-c3csc4cnccc34)oc12

HCID66760943

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 4-iodo-2-thieno[2,3-c]pyridine-3-yl-furo[2,3-c]pyridine-7-ylamine and tert-butyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidine-1-carboxylate by a procedure analogous to Example 68 followed by deprotection by a procedure analogous to Example 64, Step B. 1H NMR (400 MHz, CD3OD): δ 9.29 (s, 1 H), 8.75 (s, 1 H), 8.63 (d, J=6.1 Hz, 1 H), 8.59 (d, J=6.1 Hz, 1 H), 8.26 (s, 1 H), 8.08 (s, 1H), 7.96 (s, 1H), 7.62 (s, 1H), 5.32 (m, 1H), 4.45 (m, 4H); MS (ESI): 389.18 [M+H]+; HPLC tR=0.25 min (HPLC: Analytical—2 min).

WORKUP

后处理

customHPLC tR=0.25 min (HPLC: Analytical—2 min)