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HRID389646

反应详情

EQUATION

反应方程式

HRID 389646 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：COC(=O)[C@H](CNC(=O)c1ccc(Cl)s1)NC(=O)OC(C)(C)C
HCID67155290

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@@H](N)CNC(=O)c1ccc(Cl)s1.O=C(O)C(F)(F)F
HCID67155149

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Intermediate 8 (13.3 g, 36.66 mmol) in 75 ml DCM was treated with 25 ml TFA and stirred overnight at RT. The solvents were evaporated and the residue was dissolved in DCM and evaporated again. Yield: 21 g (TFA-salt), oil, crude material

WORKUP

后处理

  1. customThe solvents were evaporated
  2. dissolutionthe residue was dissolved in DCM
  3. customevaporated again