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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 389654Generated: October 25, 2026

Benzyl mercaptan → 1-Benzylsulfanyl-3-bromo-2-trifluoromethyl-benzene

https://huagongshe.com/reaction/389654

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl mercaptanHCID 7509—
Reactant2-Bromo-6-fluorobenzotrifluorideHCID 2773345—
Product1-Benzylsulfanyl-3-bromo-2-trifluoromethyl-benzeneHCID 67155259—

Reaction Steps

Phenyl-methanethiol (4.g g, 37.0 mmol) was treated with commercially available 1-bromo-3-fluoro-2-trifluoromethyl-benzene (10.0 g, 41.1 mmol) in close analogy to the procedure described in step 5.3). The crude product (10.5 g) after workup was used as such in the next reaction step without purification by chromatography.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08378092B2
Source datasetuspto-grants-2013_02
ORD IDord-e82cb9c16d524ad382d59b2d011bdb18
Source noteuspto-grants-2013_02