Benzyl mercaptan → 1-Benzylsulfanyl-3-bromo-2-trifluoromethyl-benzene

HRID 389654ノート

反応式

HRID 389654 の反応式
[C:1]1([CH2:7][SH:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12](F)[C:11]=1[C:17]([F:20])([F:19])[F:18]>>[CH2:7]([S:8][C:12]1[CH:13]=[CH:14][CH:15]=[C:10]([Br:9])[C:11]=1[C:17]([F:18])([F:20])[F:19])[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

3

反応物 2

HCID 7509Benzyl mercaptanHCID 27733452-Bromo-6-fluorobenzotrifluoride

生成物 1

HCID 671552591-Benzylsulfanyl-3-bromo-2-trifluoromethyl-benzene

実験手順

Phenyl-methanethiol (4.g g, 37.0 mmol) was treated with commercially available 1-bromo-3-fluoro-2-trifluoromethyl-benzene (10.0 g, 41.1 mmol) in close analogy to the procedure described in step 5.3). The crude product (10.5 g) after workup was used as such in the next reaction step without purification by chromatography.

後処理

  1. customsuch in the next reaction step
  2. customwithout purification by chromatography

出典と根拠

ORDレコード
ord-e82cb9c16d524ad382d59b2d011bdb18
出典データセット
uspto-grants-2013_02
特許番号
US08378092B2

反応ノート

読み込み中…