反应详情

Intermediate 24 (10.5 g, 30.24 mmol) was coupled with piperidin-2-one (3.597 g, 36.29 mmol) in close analogy to the procedure described in step 1.6). After workup the crude oil is purified by chromatography on silica gel (n-heptane-ethyl acetate 4:1).

1. customis purified by chromatography on silica gel (n-heptane-ethyl acetate 4:1)