HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-(2-Hydroxyacetyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-(Bromoacetyl)benzonitrile | HCID 98654 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-(2-Hydroxyacetyl)benzonitrile | HCID 17992886 | — |
Reaction Steps
A solution of 1 g of 4-(2-bromoacetyl)benzonitrile in acetonitrile (5 mL) and water (10 mL) is treated under microwave irradiation (125° C., 50 min). The same experiment is conducted five times. All the vials are collected, extracted with ethyl ether, dried over magnesium sulfate and concentrated under vacuum to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383608B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-103dc8cfdc194c609774dca0383cc9eb |
| Source note | uspto-grants-2013_02 |