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Water → 3-(2-Hydroxyacetyl)benzonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 3-(2-Bromoacetyl)benzonitrile | HCID 2735867 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 3-(2-Hydroxyacetyl)benzonitrile | HCID 18404773 | — |
反応手順
A solution of 776 mg of 3-(2-bromoacetyl)benzonitrile in acetonitrile (5 mL) and water (10 mL) is treated under microwave irradiation (125° C., 50 min). The same experiment is realized a second time with 976 mg. All the vials are collected, extracted with ethyl ether, dried over magnesium sulfate and concentrated under vacuum to give the desired compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08383608B2 |
| 出典データセット | uspto-grants-2013_02 |
| ORD ID | ord-d1b1cf9ac0ca4ef5bf8f89630d36634e |
| 出典メモ | uspto-grants-2013_02 |