Hydrazine → HCID 12366387, compound

HRID 389939Notes

Reaction equation

HRID 389939 reaction equation
[CH:1](=[C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([Br:17])[CH:15]=2)[C:10](=O)[O:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:19][NH2:20]>C(O)C>[CH2:1]([C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([Br:17])[CH:15]=2)[C:10](=[O:9])[NH:20][N:19]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 67441412HCID 67441412, compound

Product 1

HCID 12366387HCID 12366387, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of EXAMPLE 1D (778 mg, 2.58 mmol) in ethanol (10 mL) was added hydrazine (83 mg, 2.58 mmol) and the mixture was refluxed for 2 hours. After cooling, the precipitated solid was collected by filtration and dried under vacuum to yield the title compound. MS (ESI) m/z 316 (M+H)+.

Workup

  1. temperaturethe mixture was refluxed for 2 hours
  2. temperatureAfter cooling
  3. filtrationthe precipitated solid was collected by filtration
  4. customdried under vacuum

Sources & evidence

ORD record
ord-b86b2683ce9d4febae8f56342358b8ac
Source dataset
uspto-grants-2013_02
Patent number
US08383623B2

Reaction notes

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