HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 3-amino-1-[{4-(2,4-dimethylphenyl)piperazin-1-yl}propanoyl]-6-N-{(furan-2-yl)methyl}-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-amino-6-N-((furan-2-yl)methyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one | HCID 67996981 | — |
| Reactant | 3-Chloro-1-{4-(2,4-dimethylphenyl)piperazin-1-yl}propan-1-one | HCID 67997080 | — |
| Product | 3-amino-1-[{4-(2,4-dimethylphenyl)piperazin-1-yl}propanoyl]-6-N-{(furan-2-yl)methyl}-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-7-one | HCID 67997008 | — |
Reaction Steps
A target compound (187.7 mg, 0.393 mmol, 93.3%) was yielded as solid in the same manner as Example 1 by reacting 3-amino-6-N-((furan-2-yl)methyl)-5,6-dihydro-1H-pyrazolo[3,4-c]pyridin-7(4H)-one (98 mg, 0.422 mmol) with potassium carbonate (87.4 mg, 0.633 mmol) and 3-chloro-1-{4-(2,4-dimethylphenyl)piperazin-1-yl}propan-1-one (130.2 mg, 0.464 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383631B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-99897fa424134a518f41fac3a3ac8b4f |
| Source note | uspto-grants-2013_02 |