HCID 58296315, compound → HCID 58296338, compound

Participants

Reaction Steps

A round bottom flask was charged with 5-[(E)-2-(dimethylamino)ethenyl]-7-(methylthio)-1-[4-(methylthio)phenyl]pyrimido[4,5-d]pyrimidin-4(1H)-one (0.43 g, 1.30 mmol) and acetic acid (50 mL). The reaction was stirred at reflux for 18 h and acetic acid was removed under vacuum. Methylene chloride (20 mL) was added to the residue and the product was collected by filtration (0.27 g, 75% yield).

Provenance & Evidence