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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390044Generated: October 29, 2026

Trifluoroacetic acid → HCID 44818184, compound

https://huagongshe.com/reaction/390044

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86654200HCID 86654200—
SolventDichloromethaneHCID 6344—
ProductHCID 44818184HCID 44818184—

Reaction Steps

To a premixed solution of TFA (0.5 mL, 6.49 mmol) and dichloromethane (0.5 mL) was added to 1,1-dimethylethyl(3-{3-[(2-{[3-({[(1,1-dimethylethyl)oxy]carbonyl}amino)propyl]amino}-5-oxo-5,6-dihydropyrido[4,3-d]pyrimidin-4-yl)amino]phenyl}propyl)carbamate (39 mg, 0.069 mmol) and the mixture was stirred for 30 min. It was then concentrated and the product was lyophilized (30 mg, white solid).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383635B2
Source datasetuspto-grants-2013_02
ORD IDord-0322c7df847d46508154aed77d78f96e
Source noteuspto-grants-2013_02