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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390046Generated: October 29, 2026

Trifluoroacetic acid → HCID 44818185, compound

https://huagongshe.com/reaction/390046

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86654201HCID 86654201—
SolventDichloromethaneHCID 6344—
ProductHCID 44818185HCID 44818185—

Reaction Steps

To a premixed solution of TFA (0.5 mL, 6.49 mmol) and dichloromethane (0.5 mL) was added to 1,1-dimethylethyl{3-[(4-{[3-(2-aminoethyl)phenyl]amino}-5-oxo-5,6-dihydropyrido[4,3-d]pyrimidin-2-yl)amino]propyl}carbamate (11 mg, 0.024 mmol) and the reaction mixture was stirred for 30 min. It was concentrated and the product lypholized (4 mg, white solid).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383635B2
Source datasetuspto-grants-2013_02
ORD IDord-5296a0edc190427fa284c23a59ce8a93
Source noteuspto-grants-2013_02