HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 44818005, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86654202 | HCID 86654202 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 44818005 | HCID 44818005 | 133.6% |
Reaction Steps
1,1-dimethylethyl[3-({4-[(3-methylphenyl)amino]-5-oxo-5,6-dihydropyrido[4,3-d]pyrimidin-2-yl}amino)propyl]carbamate (245 mg, 0.577 mmol) was dissolved into dichloromethane (3 mL) and TFA (1 mL) was added. The reaction mixture was stirred for 1 h and concentrated. The residue was further dried under high vacuum to afford the product as a TFA salt (250 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383635B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-2396b788e5b54b66b2380d554709662b |
| Source note | uspto-grants-2013_02 |