Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390051Generated: October 30, 2026

Trifluoroacetic acid → HCID 44818005, compound

https://huagongshe.com/reaction/390051

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86654202HCID 86654202—
SolventDichloromethaneHCID 6344—
ProductHCID 44818005HCID 44818005133.6%

Reaction Steps

1,1-dimethylethyl[3-({4-[(3-methylphenyl)amino]-5-oxo-5,6-dihydropyrido[4,3-d]pyrimidin-2-yl}amino)propyl]carbamate (245 mg, 0.577 mmol) was dissolved into dichloromethane (3 mL) and TFA (1 mL) was added. The reaction mixture was stirred for 1 h and concentrated. The residue was further dried under high vacuum to afford the product as a TFA salt (250 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08383635B2
Source datasetuspto-grants-2013_02
ORD IDord-2396b788e5b54b66b2380d554709662b
Source noteuspto-grants-2013_02