反应详情

Preparation according to Preparation 22 using [7-(trifluoromethylsulfonyl)-2,3-dihydro-1,4-benzodioxin-2-yl]methanol (0.75 g, 2.5 mmol), toluenesulfonyl chloride (0.72 g, 3.8 mmol), TEA (0.42 ml, 3 mmol) and 4-DMAP (0.37 g, 3.0 mmol) in DCM (40 ml), stirred for 18 h. Yield 0.28 g. MS m/z (rel. intensity, 70 eV) 452 (M+, bp), 383 (41), 280 (82), 211 (80), 91 (84).

1. customPreparation