反应详情

温度

5 °C

A mixture of 3-(3-dimethoxymethyl-4-nitro-phenylsulfanyl)-phenylamine (0.0384 mol) and TEA (0.0576 mol) in THF (q.s.) was stirred at 5° C., and benzenesulfonyl chloride (0.0384 mol) was added dropwise at 5° C., then the reaction mixture was reacted at room temperature and purified by column chromatography over silica gel (eluent: CH2Cl2). The product fractions were collected and the solvent was evaporated to yield the title compound as a residue. (The product was used in subsequent steps without further purification.)

1. customthe reaction mixture was reacted at room temperature
2. custompurified by column chromatography over silica gel (eluent: CH2Cl2)
3. customThe product fractions were collected
4. customthe solvent was evaporated