反应详情

A solution of (S)-2-(6-methoxy-5-nitro-pyridin-2-yloxymethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester (0.11 g, 0.32 mmol) in methanol (11 ml) was hydrogenated using the ThalesNano H-Cube® hydrogenation reactor employing a 10% palladium on charcoal catalyst cartridge. After concentration of the solution under reduced pressure 0.10 g (92.6%) of the title compound were obtained.