HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 58066681, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-(1H-Pyrazol-4-yl)acetonitrile | HCID 20542700 | — |
| Reactant | HCID 58066671 | HCID 58066671 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 58066681 | HCID 58066681 | — |
Reaction Steps
(1H-Pyrazol-4-yl)-acetonitrile (0.19 g, 1.77 mmol) and N-(4-bromomethyl-3-tert-butylsulfanylmethyl-phenyl)-2,2-dimethyl-propionamide (0.20 g, 0.55 mmol) were combined in MeCN. Cesium carbonate (0.95 g, 2.90 mmol) was added, and the reaction was stirred for 45 minutes at room temperature. The mixture was worked-up and purified by silica gel chromatography to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383654B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-5d951142a32340fa98a32ed337862b90 |
| Source note | uspto-grants-2013_02 |