Lithium Hydroxide → HCID 46208546, compound

Participants

Reaction Steps

{3-[2-tert-Butylsulfanylmethyl-4-(2,2-dimethyl-propionylamino)-benzyl]-[1,2,4]oxadiazol-5-yl}-acetic acid ethyl ester (0.28 mmol) in MeOH (5 mL) was treated with 1N aqueous LiOH (0.5 mL), and the reaction was stirred for 6 hours at room temperature. The mixture was diluted with H2O and extracted with EtOAc. The combined organic layers were dried and concentrated to give the title compound.

Provenance & Evidence