Ammonia → HCID 928838, compound

HRID 390454Notes

Reaction equation

HRID 390454 reaction equation
[OH:1][N:2]=[C:3](Cl)[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1.[C:11]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)#[CH:12].N>>[C:13]1([C:11]2[O:1][N:2]=[C:3]([C:4]3[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=3)[CH:12]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 10821PhenylacetyleneHCID 53404818N-Hydroxy-3-pyridinecarboximidoyl chloride

Product 1

HCID 928838HCID 928838, compound

Procedure

The titled compound was prepared according to Method CB using the product of Example 1A (78 mg, 0.5 mmol) and 1-ethynyl-benzene (Aldrich, 52 mg, 0.5 mmol). 1H NMR (300 MHz, MeOH-d4) δ 7.37 (s, 1H), 7.46-7.68 (m, 4H), 7.85-8.00 (m, 2H), 8.37 (dt, J=7.9, 2.0 Hz, 1H), 8.66 (dd, J=4.9, 1.5 Hz, 1H), 9.10 (d, J=2.4 Hz, 1H) ppm; MS (DCI/NH3) m/z 223 (M+H)+.

Sources & evidence

ORD record
ord-386ba24d41ba41898c3bf96c9ef89e60
Source dataset
uspto-grants-2013_02
Patent number
US08383658B2

Reaction notes

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