HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 44546354, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-Methylphenylacetylene | HCID 136600 | — |
| Reactant | 5-Fluoro-N-hydroxynicotinimidoyl chloride | HCID 86636846 | — |
| Product | HCID 44546354 | HCID 44546354 | — |
Reaction Steps
The titled compound was prepared according to Method CB using the product of Example 28B (88 mg, 0.5 mmol) and 1-ethynyl-3-methylbenzene (Aldrich, 58 mg, 0.5 mmol). 1H NMR (300 MHz, MeOH-d4) δ 2.44 (s, 3H), 7.29-7.38 (m, 2 H), 7.42 (t, J=7.6 Hz, 1H), 7.64-7.81 (m, 2H), 8.17 (ddd, J=9.4, 2.8, 1.7 Hz, 1H), 8.60 (d, J=2.7 Hz, 1H), 8.97 (t, J=1.7 Hz, 1H) ppm; MS (DCI/NH3) m/z 255 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383658B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-cddee0c7d96b42bb8bc149893b94cb5a |
| Source note | uspto-grants-2013_02 |