Ammonia → HCID 44546543, compound

Participants

Reaction Steps

The titled compound was prepared according to Method CB using the product of product of Example 28B (88 mg, 0.5 mmol) and 1-(difluoromethoxy)-3-ethynylbenzene (Fluorochemicals, 84 mg, 0.5 mmol). 1H NMR (300 MHz, MeOH-d4) δ 6.95 (s, 1H), 7.31 (dd, J=8.3, 2.0 Hz, 1H), 7.47 (s, 1H), 7.59 (t, J=8.1 Hz, 1H), 7.70 (t, J=2.1 Hz, 1H), 7.77-7.83 (m, 1H), 8.18 (ddd, J=9.3, 2.8, 1.8 Hz, 1H), 8.61 (d, J=2.8 Hz, 1H), 8.98 (t, J=1.4 Hz, 1H) ppm; MS (DCI/NH3) m/z 307 (M+H)+.

Provenance & Evidence