HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 44545682, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 1-Ethynyl-4-fluorobenzene | HCID 522627 | — |
| Reactant | N-Hydroxypyrazine-2-carbimidoyl chloride | HCID 136395910 | — |
| Product | HCID 44545682 | HCID 44545682 | — |
Reaction Steps
The titled compound was prepared according to Method CB using the product of Example 83D (79 mg, 0.5 mmol) and 1-ethynyl-4-fluorobenzene (Aldrich, 60 mg, 0.5 mmol). 1H NMR (300 MHz, MeOH-d4) δ 5.70-5.81 (m, 2H), 5.85 (s, 1 H), 6.35-6.55 (m, 2H), 7.15 (d, J=2.4 Hz, 1H), 7.19-7.26 (m, 1H), 7.75 (d, J=1.6 Hz, 1H) ppm; MS (DCI/NH3) m/z 242 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08383658B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-3f1673dd1d4f4a3b8f7577d1847b4d0c |
| Source note | uspto-grants-2013_02 |