反应详情

The titled compound was prepared according to Method CB using the product of Example 83D (79 mg, 0.5 mmol) and 4-ethynyl-1,2-difluorobenzene (Apollo, 69 mg, 0.5 mmol). 1H NMR (300 MHz, MeOH-d4) δ 7.38-7.54 (m, 2H), 7.74-7.84 (m, 1H), 7.90 (ddd, J=11.1, 7.5, 2.0 Hz, 1H), 8.70 (d, J=2.4 Hz, 1H), 8.76 (dd, J=2.4, 1.6 Hz, 1H), 9.29 (d, J=1.6 Hz, 1H) ppm; MS (DCI/NH3) m/z 260 (M+H)+.