HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 390614Generated: October 29, 2026
Triethyl phosphite → Methyl (diethoxyphosphoryl)methoxyacetate
https://huagongshe.com/reaction/390614
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | Methyl chloromethoxyacetate | HCID 22034352 | — |
| Product | Methyl (diethoxyphosphoryl)methoxyacetate | HCID 85679938 | 100.7% |
Reaction Steps
26 g (186 mmol) of methyl chloromethoxyacetate and 32 mL (186 mmol) of triethyl phosphite are placed in a round-bottomed flask and heated at 150° C. for 3 hours. The reaction progress is monitored by NMR. The reaction medium is concentrated under vacuum. 45 g (100%) of methyl (diethoxyphosphoryl)methoxyacetate are obtained directly in the form of a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08383652B2 |
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| Source dataset | uspto-grants-2013_02 |
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| ORD ID | ord-f763b70300064a05a1b402dc1807d717 |
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| Source note | uspto-grants-2013_02 |
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